Antibodies for photoactive protein manipulation
- Kryptis: Biotechnologijos
The invention describes a high affinity monoclonal antibody 12B6 that specifically interacts with a photolabile DMNB moiety. This antibody is suitable for recognizing DMNB groups in proteins (and potentially other biomolecules). The interaction of the antibody and the unique DMNB group allows the manipulation of proteins labeled with photolabile groups by immunoprecipitation.
Inventors: Saulius Klima拧auskas; Rasa Rakauskait臈; Giedr臈 Urbanavi膷i奴t臈; Rita Lasickien臈, Martynas Simanavi膷ius; Aurelija 沤virblien臈
Jurisdiction: LT, EP